Purification and characterization of human recombinant IgE-Fc fragments that bind to the human high affinity IgE receptor
نویسندگان
چکیده
منابع مشابه
Purification and characterization of human recombinant IgE-Fc fragments that bind to the human high affinity IgE receptor.
The Fc-region of immunoglobulin E (IgE) comprising C epsilon 2, C epsilon 3, and C epsilon 4 domains is sufficient for binding to the alpha chain of the high affinity IgE-Fc receptor (Fc epsilon RI alpha). In order to identify the smallest Fc fragment capable of binding to the Fc epsilon RI alpha with high affinity, various regions of the IgE-Fc molecule were expressed in COS cells and investig...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1993
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)38627-2